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Aako BV
P.O. Box 205
3830 AE Leusden
The Netherlands
KvK 31009627

Nipaguard PDU

CAS number:
Propylene Glycol, Diazolidinyl Urea, Methylparaben, Propylparaben
EINECS number:
Preservative / Biocide
Non Governmental organization

General description

Nipaguard® PDU is an effective combination of Diazolidinyl Urea, Methylparaben and Propylparaben in Propylene Glycol giving excellent broad spectrum antimicrobial activity. Typical use concentrations of Nipaguard® PDU range from 0.3 % to 1 %, and the product is suitable for the preservation of a wide range of cosmetics and toiletries.


Nipaguard® PDU provides activity against gram positive and gram negative bacteria, yeasts and molds.
It is compatible with anionic, cationic and nonionic surfactants, proteins and other natural ingredients but its activity may be reduced by strong oxidizing agents and high pH (> pH 8).
Nipaguard® PDU has been successfully used to protect most types of personal care products from microbial contamination. As with other preservatives, the correct use concentration depends upon several factors, including the chemical and physical nature of the product, its ability to support microbial growth and the likelihood of recontamination during use. Experience has shown that Nipaguard® PDU will preserve cosmetics and toiletries when incorporated at concentrations from 0.25 % to 1 %. The higher concen-trations are generally required only for formulations which, by nature, are particularly difficult to preserve.
Shampoos and foam baths may be preserved with Nipaguard® PDU at concentrations between 0.25 % to 0.65 %. Products with high protein content may require levels from 0.5 % - 1 %. Other surfactant- based products, for example liquid dishwashing detergents, are generally preserved with Nipaguard® PDU over the range 0.2 %- 0.6 %. Emuslified systems, both O/W and W/O types, may be effectively preserved by the addition of Nipaguard® PDU at 0.4 %- 0.7 %. Nipaguard® PDUcan also be used to preserve sunscreen emulsions, but a decrease in activity may be observed with some organic sun screen filters.

pH stability
Nipaguard® PDU remains fully stable over a wide pH range from 3- 8.

Temperature stability
Recommended maximum handling temperature for Nipaguard® PDU is 40 °C.

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Aako BV
P.O. Box 205
3830 AE Leusden
The Netherlands
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