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Aako BV
P.O. Box 205
3830 AE Leusden
The Netherlands
KvK 31009627

Nipa Biopure 200

CAS number:
Diazolidinyl Urea
EINECS number:
Preservative / Biocide
Non Governmental organization

General description

Preservative for the cosmetic industry

Nipa Biopure® 200 is a preservative that is highly soluble in water and adaptable enough for a wide range of personal care and detergent based products.

Water (20 °C) 70 %(w/w)
Ethanol 0.01 %(w/w)
Propylene glycol 40 %(w/w)
Glycerol 36 %(w/w)



Nipa Biopure® 200 offers the following benefits:
- broad- spectrum antibacterial activity including both Gram- negative and Gram- positive bacteria
- particularly effective against Pseudomonas spe-cies and other difficult to control Gram- negative bacteria
- effective over the range pH 3.0 – 8.5
- retains activity in the presence of proteins, non-ionic surfactants and most other common ingredients of personal care products
- highly soluble in water < 60 % and readily incorporated into products

Nipa Biopure® 200 may be used in many types of personal care products including shampoos, hair conditioners, creams, lotions, baby products, eyeliners, mascaras and almost all water- based cosmetics and toiletries.
Whilst Nipa Biopure® 200 does have some limited antifungal activity, it is preferable to combine it with a recognized antifungal preservative, for example para-bens, in order to achieve a broadspectrum protection of the formulation. A synergistic blend of parabens and Diazolidinyl Urea (Nipaguard® PDU) is also available.
Nipa Biopure® 200 is typically used at concentrations from 0.1- 0.3 %.

pH stability
Nipa Biopure® 200 remains fully stable over a wide pH range from 3.0-8.5.

Temperature stability
Nipa Biopure® 200 should be incorporated during the cooling stage of hot processes. The recommended maximum handling temperature is 40 °C.

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Aako BV
P.O. Box 205
3830 AE Leusden
The Netherlands
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